Live-cell fluorescence imaging identifies bona fide reprogrammed cells. The next tools for reprogramming cells to an embryonic-like state might just be a camera and a set of fluorescently tagged antibodies. Researchers imaged more than a million human cells in vitro as they changed from skin tissue cells, known as fibroblasts, into colonies of induced pluripotent stem (iPS) cells. As expected, many similar-looking colonies appeared, but only very few consisted of fully reprogrammed iPS cells. (source: nature.com)
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