Biomedical engineers have found a way of safely delivering potentially therapeutic RNAs into vaginal cells using nanoparticles. The researchers hope similar particles could be used to make topical creams containing anti-HIV RNAs. Mark Saltzman and his colleagues at Yale University wanted to find a better way to deliver short interfering RNAs (siRNAs) into vaginal cells that might come into contact with HIV. These short snippets of RNA can be designed to repress specific genes. (source: nature.com)
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