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Promiscuous Antibody Targets Cancer Sunday, March 22, 2009 - Sarah Gingichashvili Home >> Headlines >> Cancer Research   
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Researchers have challenged an old immunological dogma — that an antibody can bind to only a single target or antigen — by engineering an antibody to bind tightly to two distinct proteins. The antibody, described in Science, blocks two proteins: vascular endothelial growth factor (VEGF) and human epidermal growth factor receptor 2 (HER2). VEGF is thought to promote growth in tumours, and HER2 is highly expressed by some aggressive breast tumours. (source: nature.com)
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