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The Resurrection of a Disease-Linked Gene Monday, March 09, 2009 - Sarah Gingichashvili Home >> Headlines >> Medicine
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A glimpse into the evolutionary history of a gene linked to Crohn's disease has revealed a bizarre example of just how dynamic genomes can be. The gene, called Immunity-related GTPase M (IRGM), seems to have been destroyed in the ancestor of Old and New World monkeys millions of years ago, only to be brought back to life again in the common ancestor of humans and great apes when a retrovirus lurking in the genome inserted itself into the gene. (source: nature.com)
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